Central Nervous System

Early Reactions

  • Skin and scalp reaction with redness, irritation, scaliness, blistering, ulceration, change in color,
  • thickening, and hair loss.
  • Nausea, vomiting, headaches.
  • Fatigue, drowsiness.
  • Altered sense of taste or smell.
  • Inflammation of ear canal or feeling of “stopped up” ear, hearing loss, dizziness.
  • Depression of blood count leading to increased risk of infection and/or bleeding.

Late Reactions

  • Permanent hair loss of variable degrees, altered regrowth, texture and color of hair.
  • Persistent drowsiness and/or tiredness.
  • Brain damage causing a loss of some degree of thinking ability or memory, or personality changes.
  • Scarring of skin.
  • Spinal cord or nerve damage causing loss of strength, feeling or coordination in any part of the body.
  • Damage of eye(s) or optic nerve(s) causing loss of vision.
  • Ear damage causing dryness of ear canal, fluid collection in middle ear, hearing loss.
  • Pituitary gland damage requiring long-term hormone replacement therapy.