• Early Reactions

    • Inflammation of bowel causing cramping and diarrhea.
    • Inflammation of rectum and anus causing soreness, spasm, discharge, bleeding.
    • Bladder inflammation causing burning, frequency spasm, pain, bleeding.
    • Skin changes: redness, irritation, scaliness, blistering, or ulceration, thickening, hair loss in treatment area.
    • treatment area.
    • Depression of blood count leading to increased risk of infection and/or bleeding.

    Late Reactions

    • Bowel wall damage causing narrowing of bowel with obstruction, ulceration or bleeding
    • which may require surgical correction or colostomy, chronic diarrhea, poor absorption of food.
    • Bladder damage with loss of capacity, increased frequency of urination, blood in urine, recurrent urinary infections, pain or spasm which may require urinary diversion and/or removal of bladder.
    • Changes in skin texture and/or coloration, permanent hair loss in treatment area, scarring of skin.
    • Bone demineralization or damage that may lead to fractures.
    • Testicular damage causing reduced sperm count, infertility, sterility or temporary risk of birth defects.
    • Impotence (loss of erection) or sexual dysfunction.
    • Swelling of the genitalia or legs.
    • Nerve damage causing pain, loss of strength or feeling in legs, and/or loss of control of bladder or rectum.
    • Fistula between the bowel or bladder and other organs.