Mantle cell lymphoma is a blood cancer that affects the body’s lymphatic system. It is considered non-Hodgkin’s lymphoma, part of the lymphoma cancer series. The origin of mantle lymphoma is our white blood cells which help in fighting against body infections.According to research, more than 70,000 people are diagnosed with lymphoma yearly in the US. Out of which, 6 percent are patients with mantle cell blood cancer. It is a rare type of non-Hodgkin lymphoma(NCL) that is hard to diagnose. In this post, we will explain this lymphoma blood cancer in detail.
What Is Mantle Cell Lymphoma?
Mantle cell lymphoma is a blood cancer affecting the body’s white blood cells. This non-Hodgkin’s cancer generally develops in the lymphocytes, which are part of the body’s immune system. The worst part of this type of cancer is that it can’t be diagnosed until it spreads throughout the body. Men over 60 are most likely to develop this type of blood cancer.
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As it affects the body’s lymphatic system, the lymphocytes start to divide and cannot fight against the infections. In other words, Mantle non-Hodgkin’s lymphoma weakens the immune system. This lymphoma cancer starts to develop in the part of the lymph node called the mantle zone. That’s why it is known as mantle cell NCL.
Understanding Mantle Cell Lymphoma ICD 10 Code
- Mantle cell lymphoma ICD 10 code is the diagnosis code used for reimbursement purposes. The diagnosis code C83.1 is the latest edition used to check the detailed stages and diagnosis process. It is a non-specific code that became effective on October 1, 2021.
- According to the deep analysis of the ICD 10 code, mantle cell lymphatic cancer involves the gastrointestinal tract. It causes multifocal lymphomatous polyposis. This cancer also shows the little diffuse pattern of mantle cell blood cancer ICD 10 with small and medium-sized lymphocytes. The effectiveness of ICD 10 non-Hodgkin lymphoma can be seen more in adults.
- The higher stages of mantle cell ICD 10 result in adult bone marrow problems. With time, non-Hodgkin lymphomas develop from either B cells or T-cells. The higher stage of mantle lymphoma is a painless enlargement of the tumors in the lymph nodes. The clinical courses for non-Hodgkin lymphoma C83.1 vary according to the morphologic type of cancer.
Mantle Cell Lymphoma Symptoms
Mantle cell lymphoma symptoms are often not seen until it spreads to other body parts. But there are early signs that might indicate this non-Hodgkin lymphoma. It starts in the lymph nodes and spreads to the other parts of the body at a faster pace. In the higher stage, this lymphoma also spreads in the liver, bone marrow, gastrointestinal tract, and blood. Here are the early symptoms of mantle non-Hodgkin lymphoma which you might notice:
Swelling In Lymph Nodes
You might notice swelling on lymph nodes during the early stage of non-Hodgkin’s lymphomas. The swollen lymph nodes result from the developing cancerous cells around the lymphatic system. The whole system and lymph nodes are essential in fighting against infections. It is the most common mantle cell lymphoma symptom in men. The lymph nodes’ swelling increases with time, weakening your immune system.
Pain In The Lower Back
The other common symptom you might face is a pain in your back. The mantle cell lymphatic cancer affects the back cells and causes pressure during movement. The pressure and pain might be low initially, but you cannot complete heavy tasks during this back pain.
Indigestion Or Abdominal Pain
This non-Hodgkin, when developed in lymph nodes, targets the other parts and causes indigestion. It is common to feel abdominal pain and ingestion as mantle cell lymphoma symptoms. However, you need to check for other reasons for this upset stomach.
Night Sweats
Night sweats or fever are common when the white blood cells are affected by this non-Hodgkin lymphoma. The level of fever is frequent, which causes sweat at night. The condition repeats every time and gets worse with time. Once you suffer from regular night sweats, it is best to go with a mantle lymphoma diagnosis.
Discomfort Due To Tonsil
It is not an early sign of mantle cell blood cancer. When cancer reaches the higher stage, it develops the small-sized tonsils around the lymph nodes. When these tonsils develop, it causes discomfort even in simple movement. On the other hand, when lymphoma spreads to another part of a lymphatic system like the spleen or liver, it creates even more discomfort.
What Is Mantle Cell Lymphoma Prognosis?
- The mantle cell lymphoma prognosis is associated with intermediate-grade non-Hodgkin lymphoma. Compared to other grade lymphomas, it is rarely curable with the standard treatment available.
- In many cases, the response rate of mantle lymphoma is 50-70%. However, this lymphoma progresses even after chemotherapy-like treatments. The median time for treatment failure might jump from 20- 18 months.
- The mantle cell lymphoma prognosis is difficult without good standard therapy. The survival rate might vary according to the stage of this blood cancer. The younger and early-stage patients have a favorable prognosis for this type of cancer.
Final Stages Of Mantle Cell Lymphoma
- The final stages of mantle cell lymphoma cause serious issues. These are the stages in which non-Hodgkin lymphoma spreads in different body parts. The lymphoma spread above or below the diaphragm and spleen.
- In other final stages of mantle cell lymphatic cancer, the disseminated disease is spread throughout multiple lymphatic organ sites, which might involve lymph nodes. Every final stage of non-Hodgkin cancer can be classified based on symptoms.
- In some cases, the final stages of mantle cell lymphoma consist of widespread diseases in other parts of the body. In these stages, the cancer cells grow beyond lymph nodes and affect the spleen, bone marrow, and other organs. The mantle cell lymphatic cancer also affects the liver and digestive tract. It is recommended to consult with a cancer specialist in the final stages of this cancer.
What Is The Survival Rate Of Mantle Cell Lymphoma In Men?
Most people are confused about the survival rate of mantle cell lymphoma in men? The survival rate of mantle cell lymphatic cancer is lower than the other types of cancer. The reason is the difficult diagnosis of this cancer in the early stages. However, advanced research and treatment showed an improvement in the survival rate among men.
- The survival rate of mantle cell lymphoma in men is about 3-5 years. That means around 50% of people who suffer from MCL have a life expectancy of 3-5 years.
- Suppose we talk about the ten-year survival rate of lymphatic cancer. The ten-year survival rate of MCL in the mean is between 5-10 percent. It means 5-10 people out of 100 can live for ten years.
- The survival rate of mantle non-Hodgkin lymphoma changes due to the advanced diagnosis and treatment. It would be difficult to say the exact survival rate of this disease among men. The positive effects on life expectancy can be seen in patients in the final stage of Mantle non-Hodgkin cancer.
Conclusion
Mantle cell lymphoma is cancer that targets the lymphatic system of the body. In most cases, it shows rare or no signs in the body. However, men over 60 likely develop this type of blood cancer. Some early symptoms people notice are swollen lymph nodes, abdominal pain, and night sweats. The survival rate of this non-Hodgkin cancer is lower than other types of cancer. It is suggested to consult with a doctor when you notice the early signs of this cancer.
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