Uterine cancer is a type of cancer that starts in the uterus when the endometrium gets out of control and crowds normal cells. The endometrial (uterine) cancer cells move quickly to all other body parts like the liver or vagina and begin to grow there. It is known as metastasis when cancer cells spread to other areas. However, the cancer type is based on the kind of site it begins. So when endometrial cancer spreads from the uterus to the liver (or other places), it is known as endometrial or uterine cancer. The uterine cancer stage 1 survival rate varies with each treatment method.
What Do We Mean By The Endometrium?
The pear-shaped organ in the woman’s lower belly that holds a baby in pregnancy is known as the uterus. The uterus’s inner lining is known as the endometrium. In 4 weeks, a woman’s hormones make the endometrium thick and ready for pregnancy. When no pregnancy exists, the endometrium emerges from the woman’s vagina as her period. (The vagina links the uterus outside of the body.)
Stage 1 Uterine Cancer
Cancer doesn’t go outside the uterus at this stage. It also affects the cervix glands, a thin channel at the uterus bottom.
Stage 1A: Cancer moves to the endometrium, the uterus’s inner lining. It is possible that it went only halfway into the muscle beneath.
Stage 1B: The malignancy moves across the endometrium and up to half of the core muscle affecting the uterine cancer stage 1 survival rate.
Unusual bleeding, like bleeding and spotting between menstrual cycles, is the main symptom. The vaginal discharge can be blood-tinged or watery with a foul smell.
The typical treatment is hysterectomy which increases the uterine cancer stage 1 survival rate. It removes the uterus’s cervix, ovaries, and fallopian tubes. The surgeon performs pelvic cleaning. Then flushes the abdomen with a saltwater solution. Later they test it for cancer cells.
Surgery can be a good option for some females to improve uterine cancer stage 1 survival rate. However, you might need therapy for more enormous masses or cancer that moves. Cancer cells may go out of the uterus. Chemotherapy, vaginal brachytherapy, and radiation therapy, allotting the radioactive material to cancer cells can be good for avoiding cancer relapse.
For stage 1A, endometrial cancer, you can get progestin treatment if you want to have kids. All these hormones can shrink or vanish malignancy for some time, letting you become pregnant. If you are not careful, this choice will be hazardous. Sometimes, the hormones don’t function properly, leading to cancer growth. As women with Stage 1 uterine cancer don’t have cancer moving beyond their uterus, many treatment options have different uterine cancer stage 1 survival rates.
Stage 1A is cancer limited to the inner layer of cells of the uterus (endometrium). Cancer (Stage 1B) spreads to less than half of the uterus muscle wall. Stage 1C is cancer that takes up around half of the uterus muscle wall impacting the uterine cancer stage 1 survival rate.
For most patients, doctors can cure the condition with surgery alone to improve the uterine cancer stage 1 survival rate. The best treatment would need more therapeutic methods for the situations. Thus, it would be vital for the patients to be treated at a medical center with multi-modality treatment from radiation oncologists and gynecologic oncologists.
The standard treatment for stage 1 uterine cancer is a total abdominal hysterectomy (uterus removal) and bilateral salpingo-oophorectomy (removal of ovaries and fallopian tubes) with or without removing para-aortic and pelvic lymph nodes. Stage 1 cancer has microscopic cells known as micrometastases that later spread out of the uterus. Thus, doctors can’t remove it with surgery, impacting the uterine cancer stage 1 survival rate. Despite surgical resection of cancer, around 5 to 20% of patients get cancer relapses.
The cancer cells don’t detect any of the tests impacting the uterine cancer stage 1 survival rate. The presence of micrometastases leads to relapses after the surgery.
Survival Rate Of Stage 1 Uterine Cancer Surgery Treatment
Patients with stage 1 endometrial carcinoma, with a total abdominal hysterectomy, bilateral salpingo-oophorectomy (TAH-BSO), and the postoperative radiotherapy (RT), tailored to the prognostic facts, have uterine cancer stage 1 survival rate of 80% to 90% as five-year rates, and 5-year for the survival rate of uterine cancer stage 1 of 90% to 95% with 4% to 8% relapse rates. However, patients with grade 3 tumors with deep (50% or more) myometrial invasion (stage IC, grade 3) have a high risk of distant and loco regional relapse.
The Gynecological Oncology Group (GOG) staging study showed a risk of microscopic pelvic node metastases for patients with stage 1. A clinical study found microscopic pelvic nodes spread for the patients with clinical stage 1 endometrial carcinoma to be less than 10% except for those with 33% outer myometrial invasion for 18% of risk people.
Adjuvant therapy is a cancer treatment that includes local surgery, radiation therapy, chemotherapy, and biologic therapy. Although it is still taken in clinical trials, most stage 1B and 1C uterine cancer patients often get adjuvant radiation therapy. After surgical removal of the uterus, doctors sew together the “vaginal cuff.” The vaginal cuff is a typical local cancer recurrence site after the treatment with surgery, affecting the uterine cancer stage 1 survival rate.
Radiation therapy kills any left-out cancer cells post-surgery. Stage 1 uterine cancer with surgery and postoperative radiation therapy has an 80 to 90% recurrence rate with only a 4 to 8% local relapse rate. Adjuvant radiation therapy needs brachytherapy or/and external beam radiation.
The Brachytherapy treatment involves placing a radioactive isotope into the vagina and might have fewer side effects than external beam radiation. The brachytherapy has radiation therapy at a high dose rate within three weeks of treatment to the “vaginal cuff” area. ‘
Florida-based researchers also found 396 women’s outcomes with the hysterectomy stage 1 uterine cancer treatment, including lymph node dissection and brachytherapy. Following the 5-year, the uterine cancer stage 1 survival rate was 100% of the patients with 97% survival rate for stage 1A, stage 1B, and 93% for stage 1C.
But as all trials don’t directly compare the brachytherapy to brachytherapy + hysterectomy, it is unknown whether the brachytherapy and hysterectomy improve uterine cancer stage 1 survival rate than only the surgery. It happens as a local cancer treatment recurs in patients with surgery, possibly with further radiation and surgery.
Adjuvant External Beam Radiation Therapy
Surgeons offer external beam radiation therapy (EBRT) with machines named linear accelerators. They offer high-energy external radiation beams that penetrate the tissues and deliver the radiation dose deep in areas with cancer.
The large clinical trials of 715 women with stage 1 uterine cancer matched treatment with surgery alone or after adjuvant external beam radiation therapy.
Study Survival Rate
Such women had deep muscle invasion of the uterus and a high grade of hostile cancer types. However, the uterine cancer stage 1 survival rate was around 81% for adjuvant radiation therapy and only 85% for surgery.
Although the patients with radiation and surgery survived for a long time, more side effects are in women with radiation therapy. Doctors concluded that postoperative radiation therapy lessens local cancer recurrences following the stage 1 uterine cancer surgery, but it didn’t progress the survival rate of uterine cancer stage 1.
Treatment after radiation therapy or surgery only for 5 to 20% of patients with local cancer recurrence spares most women with stage 1B and 1C uterine cancer from the radiation treatment. Timely examinations are essential to determine the uterine cancer stage 1 survival rate for patients who didn’t get radiation therapy. Thus, it’s best to find any cancer removal treatment early. University Cancer Centers is dedicated to extensive research and developments in the field of cancer and offers the best in class medical technology and perfect treatment ways to improve survival rates. Our medical team ensures that they keep the patient under 24×7 care and observation and leave them home after fully recovering.